Innovation Voucher Program
Mission critical instruments, equipment and expertise now available at UMass
Get discounted access to the resources you need to efficiently develop and test products
A new Innovation Voucher Program is providing innovative growth companies headquartered in Massachusetts access to 90 UMass core research facilities throughout the state. The program:
- Reduces the time it takes to access resources
- Ensures that companies retain their intellectual property
- Reduces the cost to develop and test products
UMass core research facilities are available at daily or hourly rates or per unit rates. Approved voucher requests from companies with 10 or fewer employees get a 75% discount, and companies with 11-50 employees get a 50% discount. A total of $2 million in vouchers is available, first come, first served. $75,000 is the maximum voucher amount an individual company may be awarded in any one year.
Select core facilities available in Boston
These facilities are located in the Integrated Sciences Complex (ISC), opened in Spring 2015 (when most of the equipment was purchased) on the UMass campus at 100 Morrissey Blvd. in Boston. It is a 30 minute trip door-to-door on the Red Line from Kendall to UMass. For your convenience, a new 1,400 parking garage adjacent to the ISC is opening in 2018.
The 7,515 square foot Animal Vivarium is located on the 5th floor of the ISC, and comprises:
- 16 housing rooms, independently controlled housing cubicles, pass-through cage washer and autoclave, operation room, one necropsy room, three procedure rooms
- Staffed 7-days a week and offers routine husbandry and breeding care for the animals.
The lead is Elizabeth Boates (Animal Care Technician). Learn more.
Broad Spectrum Molecular Imaging
The Broad Spectrum Molecular Imaging Core is located on the 4th floor of the Science building and comprises:
- Multi-integrated system including a Bruker micro-FTIR/micro-Raman spectrometer, femtosecond ASOPS system, and cryogen-free refrigeration system. It permits the spectral assessment of a wide variety of biological materials ranging from tissues to complex mixtures in the very far IR, near IR, visible and UV spectral ranges.
CPCT (Molecular Biology) Shared Equipment
The Center for Personalized Cancer Therapy Shared Equipment Core is located in 4610, 4612, 4613, 4614, 4615 and 4640 ISC. Multiple pieces of equipment available:
- LiCor Odyssey digital imaging station
- c-Digit chemiluminescence system
- EVOS cell imaging system
- Shaker incubators
- Thermal cyclers
- 4 laminar flow hoods
- 4 CO2 incubators for mammalian cell culture
- Mini flow cytometer
- Visible and fluorescence plate readers
The faculty lead for this Core is Jill Macoska, PhD (Biology). Associated cancer biology faculty in the CPCT are Changmeng Cai, PhD (Biology); Shailja Pathania, PhD (Biology); Jason Evans, PhD (Chemistry); Catherine McCusker, PhD (Biology); Kellee Siegfried, PhD (Biology); and Alexey Veraksa, PhD (Biology). They focus on RNA- and protein-based cancer biomarkers with significant clinical utility.
The Fabrication Core is located on the 3rd floor of the Science building and comprises:
- Objet30 3D Printer (which permits the printing of objects from biocompatible materials)
- Roland MDX-540SA milling instrument
- Markforged Mark 2, a 3D printer capable of printing continuous carbon fiber reinforced parts
- Ultimaker 2, a fused deposition modeling 3D printer
- GCC LaserPro Spirit LS
The faculty lead for the Fabrication Core is Filip Cuckov, PhD (Engineering).
The Imaging Core is located in 4200 ISC and comprises:
- Zeiss LSM 880 Confocal Microscope which permits high-resolution 3D imaging of biological specimens
- Olympus BX53 upright and IX73 inverted fluorescence microscopes
The faculty lead for this Core is Alexey Veraksa, PhD (Biology). Associated biomedical imaging faculty are Walter Buchwald, PhD (Engineering); Matthew Bell, PhD (Engineering); Jonathan Rochford, PhD (Chemistry); and Chandra Yelleswarapu, PhD (Physics).
See Environmental Analytical Facility for JEOL JSM-6010LA IntouchScope Scanning Electron Microscope, and Smiths Detection FTIR Microscope.
See CPCT Shared Equipment for LiCor Odyssey digital imaging station, and EVOS cell imaging system.
See Animal Vivarium Barrier Suite for Perkin Elmer IVIS Lumina XRMS Series III In Vivo imaging system.
Mass Spectroscopy (Proteins)
The Mass Spectroscopy Core (Proteomics) is located in 3410 ISC and comprises:
- Nanoflow HPLC-high resolution mass spectrometer system with Thermo-Forma EASY-nLC 1200 System
- Orbitrap Fusion Lumos Tribrid Mass Spectrometer for high pH reversed phase fractionation of protein digest to support 2D-LC-MS-MS applications
- UltiMate™ NCP3500RS HPLC system
- Proteome Discoverer 2.0, ProSight PC 3.0 and Sieve 2.0 analytic software
The faculty lead for this Core is Jason Evans, PhD (Chemistry) and technical support is provided by Dennis Zeh, a Chemistry doctoral student.
There is a Bruker MALDI-TOF in the Venture Development Center, 3rd floor, Wheatley.
Animal Vivarium Barrier Suite
The Animal Vivarium Barrier Suite allows for the housing and use of immunocompromised mice, the standard in vivo model for tumor xenografting in cancer research. Includes:
- Getinge GE6613 ERB 2 Door Steam Sterilizer solely for the autoclave sterilization of immunocompromised mouse cages, water bottles, bedding, and other husbandry components
- Perkin Elmer IVIS Lumina XRMS Series III instrument that permits visualization of tumor growth, response to chemotherapeutic agents, and assessment of tumor biomarkers in vivo and in real time without the need to sacrifice the host animal
The faculty lead is Jon Celli, PhD (Physics).
High Performance Computing
The High Performance Computing Core is located in 4610 ISC and UMass Boston Data Center in the Science building. The Core provides:
- Data storage on a mirrored redundant array of independent disks in the Data Center
- Data transfer between the Genomics Core and the Massachusetts Green High Performance Computing Center at Holyoke, MA
- High Performance Computing Node (2 multi-core Xeon E5-2600 series processors and C602 chipset with four hot-swap 3.5 SAS/SATA hard drive bays)
MGHPCC is a 90,000 square foot, 15-megawatt facility. With high-end computing equipment and storage, including thousands of CPU cores and GPU cards, UMass operates one of the biggest GPU clusters in the nation.
The faculty lead of this Core is Todd Riley, PhD (Biology).
Environmental Analytical Facility
The Environmental Analytical Facility houses a suite of state-of-the-art instrumentation for characterizing elements and compounds, and is located in ISC on the 2nd and 3rd floors. It comprises:
Isotope Ratio Mass Spectrometer (IR-MS)
- Thermo Delta V+ IR-MS with universal triple collector
- Thermo Gas Bench II for isotopic analyses of water, dissolved inorganic carbon, and carbonate minerals
- Costech Elemental Analyzer ECS 4010 for carbon, nitrogen and sulfur isotopic analyses in solids
- Ocean Analytical Wet Oxidation Total Organic Carbon Analyzer for carbon isotopic measurements of dissolved inorganic and organic carbon
- Thermo GC Isolink and Trace GC Ultra for compound specific carbon and nitrogen isotope measurements
Gas Chromatography Mass Spectrometer (GC-MS)
- Thermo DSQ II MS
Inductively Coupled Plasma Mass Spectrometer (ICP-MS)
- PerkinElmer ELAN DRCII
- ICP-MS peripherals and processing equipment
- Solid sampling: Cetac LSX 213 (213 nm Nd:YAG) equipped with cryogenic laser ablation cell, low volume cells and large format cell
- Speciation: SRI portable GC and heated transfer line
- Liquid Sampling: Autodilution autosampler, Scott and Cyclonic spray chambers including small volume, teflon, etc., Meinhard and cross-flow nebulizers including microvolume, Aridus desolvating nebulizer
- Pre-concentration and extraction systems for low-level trace metal analyses including HPLC fraction collection system
- In-field trace metal clean water collection systems
- JEOL JSM-6010LA IntouchScope Scanning Electron Microscope
Elemental Analyzer (EA)
- Costech Elemental Analyzer ECS 4010 for carbon, nitrogen and sulfur isotopic analyses in solids
- PerkinElmer EA: NC of solids
Cold Vapor Atomic Flourescence Spectroscopy (CVAFS)
Fourier Transform Infrared Spectroscopy (FTIR)
- Smiths Detection FTIR Microscope
Liquid Nutrient Analyses
- Lachat QuickChem 8500 FIA
- Cetac QuickTrace M-8000
- Cetac QuickTrace M-6100
Sediment Digestion Systems
- CEM MARS microwave digestion system
- SCP Digiblock system
- Phoenix 8000 organic carbon analyzer
- Turner 10AU Field and Laboratory Fluorometer
- Spectro XEPOS Bench Top Energy Disperson X-ray Fluorescences
The Flow Cytometry Core is located in 5500 ISC and comprises a Becton Dickinson FACS Aria III for live cell sorting and cell counting. The instrument is located in a biosafety cabinet to contain potentially aerosolized materials. The BD FACS Aria Fusion has precisely integrated fluidic and optical systems to maximize signal detection. Optimized fiber-launched lasers improve sensitivity and resolution for each color in a multicolor assay.
The faculty lead for the Core is Cate McCusker, PhD (Biology).
A self-service option is the benchtop Sony SH800 which permits sorting of a wide range of cell sizes for many applications using microfluidics sorting chips. It is located in the Venture Development Center, 3rd floor, Wheatley.
The Genomics Core is located in 4630 ISC and provides services for traditional capillary sequencing, high-throughput next-generation sequencing, library preparation, and various data analyses. It comprises:
- Illumina HiSeq 2500, capable of DNA/RNA high throughput sequencing
- cBot Cluster Generation System
- Illumina MiSeq
- 10X Genomics Chromium Controller for single cell profiling enables the discovery of previously inaccessible genetic information at massive rate and scale
- Qubit 2.0 for DNA/RNA quantitation
- Agilent Bioanalyzer for DNA/RNA integrity assessment
- Covaris DNA fragmentation instrument
- Beckman Coulter FXP Dual Multichannel Span-8 robot to automate sequencing library preparations
- NanoString nCounter system which utilizes a novel digital color-coded barcode technology that is based on direct multiplexed measurement of gene expression and offers high levels of precision and sensitivity, ideal for the quantitation of RNA-based nucleic acids in solid and liquid biopsies, and is FDA-approved for clinical diagnostics.
The faculty lead for this Core is Jill Macoska, PhD (Biology). Associated genomics and bioinformatics faculty are Rahul Kulkarni, PhD (Physics); Todd Riley, PhD (Biology); and Kourosh Zarringhalam, PhD (Mathematics). Learn more.
Sign up now, vouchers are first come, first served
Please complete this form to access any or all UMass core facilities. The appropriate UMass campus contact will get right back to you to answer your questions, scope the project and determine the voucher amount.